Job Description

Dovetail Therapeutics is seeking a talented and motivated Senior/Principal Scientist to join our growing and dynamic team. If you are passionate about developing new technologies and contributing to the next generation of biotherapeutics in a collaborative and fast-paced environment where your contributions will make a real difference, this role is for you.

Key Duties and Responsibilities:

• Lead and contribute to discovery and optimization efforts for antibody candidates
• Work with internal cross-functional teams and CROs to design and advance novel biotherapeutics
• Develop and implement innovative strategies and methodologies to accelerate antibody discovery and engineering workflows
• Analyze and effectively communicate ideas and findings to internal stakeholders

Knowledge and Skills:

• Expertise in antibody and protein science, molecular biology, and biotherapeutic discovery
• Hands-on experience in therapeutic protein and antibody engineering, particularly with optimization of molecular properties, affinity maturation, and/or antibody humanization
• Proven ability in applying state-of-the-art antibody engineering approaches and computational tools to shape design strategy and optimize workflows
• Skilled in sequence analysis and structural modeling for protein design
• Ability to synthesize functional and biophysical data and integrate high-throughput datasets to guide selection and engineering strategies
• Stay current on emerging trends in protein design and introduce innovative techniques to expand team capabilities

Qualifications:

• Ph.D. degree in structural biology, molecular biology, biochemistry or a related field
• 5+ years of experience in antibody discovery and protein engineering in an academic or industry setting; 2+ years of industry experience strongly preferred
• Excellent organizational and communication skills with attention to detail
• ·Ability to work in a fast-paced, interdisciplinary environment

About Dovetail Therapeutics:

Dovetail Therapeutics is bringing life-changing therapies to patients through its novel, next generation technologies. We are located at 1616 Eastlake Ave East in the vibrant South Lake Union area of Seattle. We foster a culture of collaboration and innovation in which every employee plays a critical role in shaping our success. Dovetail offers a competitive total compensation and benefits package. Benefits include medical, dental and vision coverage, paid parking or transit, a 401(k) plan, and paid time off, among other components.