Job Description

This is a wet lab-based position at the Genomics and Integrative Biology Group within UCB Biosciences based in Durham, NC. This is an in-person position with the expectation of being in the lab 5 days a week.   The role contributes at an in vitro technical level to design studies, produce and interpret data and contribute to current and future drug discovery projects.  Skills should include molecular and cell biology knowledge together with previous experience of a range of in vitro based technology capabilities and screening approaches.

Primary responsibilities :

• Design and execution of functional genomics assays/screens to identify and validate novel targets including assessment of relevant biology in screening models, and validation of hits
• Development of novel in vitro assays for functional genomics screens
• Develop cell models for muscle disease modeling that can be used with functional genomics assays
• Provide scientific insight on projects in consultation with UCB on functional genomics (medicinal chemists, cell biologists, disease area experts, antibody engineers, etc.)
• Provide strong scientific thinking, develop hypotheses and drive scientific learnings on projects/functional genomics platform

Education and experience:

• Scientist I:  BS with 5+ years industry experience OR Masters with 1-3 years industry experience or PhD (0-2 years experience) in applicable field
• Scientist II: BS or MS with 10+ years of industry experience or PhD in applicable field with 2+ years of postdoc industry experience
• Experience in working with in vitro models of muscle cell biology and/or neuromuscular diseases
• Experience of applying cellular and biochemical techniques for target identification, validation, genetic screening and evaluating the mechanism of action of novel molecular entities
• Experience in molecular biology approaches and advanced cell biology techniques (flow cytometry, gene and protein analysis, PCR, cloning, lentiviral library prep)
• Excellent communicator, with demonstrated ability to work across disciplines
• Ability to work independently and manage priorities and engage in a multidisciplinary environment

Preferred experience:

• Experience in single cell analysis
• Experience in in vivo models for Neuromuscular Disorders

Salary:   This position’s reasonably anticipated base salary range is $88,000 to $115,500 per year. The actual salary offered will consider internal equity and may also vary depending on the candidate’s region, job-related knowledge, skills and experience, among other factors.