Job Description

Description

PRIMARY OBJECTIVES: Perform and lead cross-functional laboratory assays with a focus on in vitro/In vivo studies. Assist in the development and execution of novel assays including collecting, processing and communicating data.

Duties And Responsibilities

• Contribute to the development of SOPs and assay workflows for pre-clinical and clinical assays.
• Contribute to data processing and preparation for client presentation.
• Perform basic and advanced cell culture to characterize growth and survival under treatment by client test agents through the use of 2-D and 3-D cell-based assays.
• Lead small scale projects that are specific to cell- banking or operations.
• Contribute to the development and execution of 3-D co-culture assays including primary, PDX, and immune cells.
• Efficiently plan and execute cell line scheduling for in vivo studies.
• Perform molecular biology endpoints including qRT-PCR, ELISA, Western Blot, and Luminex.
• Responsible for operating and assisting in development of high throughput automated laboratory systems including liquid handlers, dosing units, plate readers, and high content imaging equipment.
• Documentation and maintenance of laboratory and supply inventory by working with facilities and procurement team.
• Communicate the scientific outcomes of experiments/projects between teams in a clear and detailed manner.
• Contribute to the culture of the ex vivo group by demonstrating high performance, sporting accountability and fostering collaboration and teamwork.
• Other duties may be assigned verbally at any time.
  

Qualifications

KNOWLEDGE, SKILLS, AND ABILITIES

• Expertise and well versed in cell culture and cell-based assays.
• Proficiency handling primary cells, tumor tissue, and various blood products including serum/plasma, whole blood, and PBMCs.
• Proficiency with one or more additional molecular biology techniques including qRT-PCR, ELISA, Western Blot, and Luminex.
• Experience with flow cytometry and sequencing is preferred but not required.
• Experience managing small-scale projects and maintaining strong communication skills are required.
• Demonstrated ability to work effectively and productively in a team-oriented environment while maintaining a strong sense of integrity and confidentiality.
• Creative problem-solving skills and the ability to exercise sound and accurate judgment in making timely decisions.
• Strong planning, organizational, computer, written and verbal communication skills.
• Demonstrated accountability, initiative, and responsibility for own work.
• Ability to observe safety and security procedures.
• Ability to assist with other tasks/duties as needed in a small company environment.
  

Education

EDUCATION AND EXPERIENCE

• BS or MS degree with 2-4 years of relevant experience required. Preferred field of study in biology, or related sciences.
• Laboratory based experience and knowledge of aseptic technique/cell culture is required.
  

PHYSICAL DEMANDS AND WORK ENVIRONMENT (for lab personnel)

• Must be able to sit and use hands to finger, handle and feel.
• Must be able to lift and move packages weighing up to 50 pounds.
• Some activities require repetitive motion and reaching, pulling or pushing.
• In carrying out the duties of the job there will be frequent exposure to fumes and chemical hazards.
• Duties performed routinely require exposure to blood, body fluid and tissue.
  

PHYSICAL DEMANDS AND WORK ENVIRONMENT (for office-setting personnel)

• Must be able to sit for long periods of time using a computer in a typical office environment in a multi-level facility