Senior Scientist, Lead Identification and Optimization (LIDO) – Novartis – USA
Job Overview
-
Date PostedMarch 18, 2026
-
Location
-
Expiration dateApril 17, 2026
-
Job Description
We are seeking a highly motivated, detail-oriented and experienced biology expert to join our Lead Identification and Optimization (LIDO) teams at our research site in Cambridge (MA, US). You will accelerate drug discovery by producing high quality data on compounds tested in cellular and biochemical profiling assays, working closely with your colleagues in global Discovery Sciences (DSc) and project teams within Biomedical Research (BR) located in Cambridge and Basel.
You are a self-motivated, curious, creative and agile biologist with strong experience in developing cellular and/or biochemical profiling assays to support the early drug discovery flowchart. You enjoy lab work and process improvement as well as supervising students. You enjoy working in a collaborative, fast-paced environment and want to positively impact drug discovery through advancing early hits into drug discovery development candidates.
About the Role
Internal Job Title: Senior Scientist I/II
Position Location: Cambridge, MA onsite
- Novartis is unable to offer relocation support for this role: please only apply if this location is accessible for you. #LI-onsite
We are seeking a highly motivated, detail-oriented and experienced biology expert to join our Lead Identification and Optimization (LIDO) teams at our research site in Cambridge (MA, US). You will accelerate drug discovery by producing high quality data on compounds tested in cellular and biochemical profiling assays, working closely with your colleagues in global Discovery Sciences (DSc) and project teams within Biomedical Research (BR) located in Cambridge and Basel.
Key responsibilities:
- Adapt biochemical and/or cellular profiling assays into robust and standardized assays to support testing of newly synthesized compounds generated by project teams with a focus on fast turnaround times with regards to delivering data.
- Develop, document and maintain SOPs for LIDO process and quality control.
- Proactively identify and implement improvements to enhance lab processes, performance and reliability.
- Coordinate and plan execution of LIDO profiling assays with internal stakeholders.
Essential Requirements:
- BS or MS in Biology, Biochemistry, or equivalent qualifications, with 5+ years’ relevant experience
- Strong expertise in either biochemical or cellular assay development.
- Proven experience in executing profiling assays in a drug discovery organization.
- High attention to detail and commitment to operational excellence.
- Strong organizational and time-management skills.
- Ability to work independently and collaboratively within multidisciplinary global teams.
- Flexibility and responsiveness to shifting priorities.
- Excellent written, verbal, and interpersonal communication skills.
The salary for this position is expected to range between $93,800 and $174,200 per year for Senior Scientist I, and $98,700 and $183,300 for Senior Scientist II. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.
Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.
US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.