Job Description

We’re Hiring! Join Our Team in Viral Vector Downstream Processing 🧬
Are you an expert in Viral Vector Downstream Process looking for your next exciting opportunity? We’re expanding our team and looking for professionals with hands-on experience in viral vector purification, product recovery, and process optimization.
🔹Position: Research Scientist
🔹 Location: Faridabad
🔹 Experience Required: 3 to 4 years in viral vector downstream processing
🔹Qualification: M.Sc./M.Tech./Ph.D. (Virology/Life-Sciences/Biotechnology/Genetic Engineering/Cell Biology)
Key Responsibilities:
🔹Design, optimize, and scale viral vector purification processes (Retrovirus, Lentivirus, etc.)
🔹Execute chromatography, filtration, and other purification techniques
🔹Develop and implement strategies to improve yield, quality, and efficiency
🔹Collaborate cross-functionally with upstream, quality, and regulatory teams
🔹Ensure compliance with industry regulations and Good Manufacturing Practices (GMP)
What We’re Looking For:
🔹Proven experience in viral vector production and downstream processing
Purification Techniques:
🔹Ultrafiltration & TFF (Tangential Flow Filtration): Knowledge of TFF and ultrafiltration for concentrating viral vectors, removing host cell proteins, and ensuring high yield and purity.
🔹Density Gradient Centrifugation: Proficiency in CsCl or other gradient centrifugation techniques for separating viral particles from contaminating host cell material.
🔹Viral Titer Determination: Proficiency in methods for accurately determining viral titers, such as qPCR, ELISA, and infectivity assays (e.g., viral infectivity and transduction efficiency assays).
🔹Chromatography: Expertise in using affinity chromatography, ion exchange chromatography, and size-exclusion chromatography to purify retroviral and lentiviral vectors.
🔹Flow Cytometry: Expertise in using flow cytometry for analyzing viral vector transduction efficiency and titers, particularly for retroviral and lentiviral vectors.
🔹Familiarity with regulatory requirements (GMP, FDA, EMA)
🔹Excellent problem-solving and communication skills

Interested and qualified candidates kindly share your CV to priyanka.chaudhary@eastocyonbio.com , rohit.rajput@eastocyonbio.com indra.dev@eastocyonbio.com